Fig. 1.

Rescue of fz^P21 Dfz2^– homozygotes by ΔCRD forms of Fz and Dfz2. (A and B) Full-length and ΔCRD forms of Dfz2, with the positions of the Dfz2^C1,2,3 and ^-4 mutations, as well as the corresponding position of the fz^P21 mutation, indicated (see Materials and Methods). (C and D) Ventral larval cuticles formed by wg^CX4 and fz^P21 Dfz2^– homozygotes: Both form lawns of ventral hairs, the hallmark phenotype corresponding to lack of Wg signal transduction. (E and F) Ventral larval cuticles formed by fz^P21 Dfz2^– homozygotes carrying the Tubα1-fz^ΔCRD (E) or Tubα1-Dfz2^ΔCRD (F) transgene: Both show normal, segmented patterns of ventral hairs.