Figure 2.

Patient A, female, 61 years old. She complained of dizziness and memory loss, but had no risk factors of cerebrovascular diseases. Citicoline therapy (0.6 g/d) was performed for 1 year. TrackVis software displayed the fasciculi in the white matter. A displays LA of Fazekas grade 3; A1 displays the DTI image at baseline; A2 displays the DTI image after 1-year treatment. The number of fasciculi in the white matter in A2 was slightly lower than in A1. Red: transverse fasciculi in the white matter; blue: longitudinal fasciculi in the white matter. DTI = diffusion tension imaging, LA = leukoaraiosis.