Fig. 2.

Map of human imprinted domains known to be associated with disease. Paternally expressed genes are shown on the left side of the chromosome and maternally expressed genes are shown on the right side of the chromosome (parent of origin-specific expression of GRB10 is different in different tissues). Associated conditions are shown under the chromosome. TNDM1 is transient neonatal diabetes mellitus (TNDM1), RSS is Russell–Silver syndrome, BWS is Beckwith–Wiedemann syndrome, KOS is Kagami-Ogata syndrome, TS is Temple syndrome, AS is Angelman syndrome, PWS is Prader-Willi syndrome, and PHP1a&b are pseudo-hypoparathyroidism types 1a&b.