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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: J Endocrinol. 2017 Jan 5;232(3):461–474. doi: 10.1530/JOE-16-0484

Figure 1.

Figure 1

Effects of 12 days of sc leptin infusion on serum leptin (A), uncoupling protein-1 (UCP-1) gene expression in brown adipose tissue (BAT) (B), food intake over duration of treatment (C), cumulative food intake (D), body weight over duration of treatment (E), abdominal white adipose tissue (WAT) weight (F), blood glucose (G) and uterine weight (H) in female ob/ob mice (n=8/group). Please note the expected dramatic decrease in food intake in ob/ob mice associated with transfer from room temperature to thermoneutral housing (Iwaniec et al. 2016). Data are mean ± SE. aDifferent from vehicle-treated ob/ob mice (ob/ob), P<0.05. WT is shown as a reference group.