Table 1. Definitions of metabolic syndrome according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATPIII), the International Diabetes Federation (IDF), the American Heart Association (AHA), and the World Health Organization (WHO).
NCEP ATPIII [21] | IDF [26] | AHA [9] | WHO [23] | |
---|---|---|---|---|
Definition | ≥3 risk factors | Increased waist circumference plus ≥2 risk factors | ≥3 risk factors | DM/IFG or IGT or IR plus ≥2 risk factors |
Risk Factor | ||||
Abdominal Obesity | Waist circumference: >102 cm (>40 in) in men; >88 cm (>35 in) in women | Waist circumference: dependent on ethnicity | Waist circumference: >102 cm (>40 in) in men; >88 cm (>35 in) in women | Waist circumference: dependent on ethnicity |
Triglycerides | ≥150 mg/dL (≥1.7 mmol/L) or drug treatment for elevated levels | ≥150 mg/dL (≥1.7 mmol/L) or drug treatment for elevated levels | ≥150 mg/dL (≥1.7 mmol/L) or drug treatment for elevated levels | ≥150 mg/dL (≥1.7 mmol/L) |
HDL cholesterol | ||||
Men | <40 mg/dL (<1.0 mmol/L) or drug treatment for reduced levels | <40 mg/dL(<1.0 mmol/L) or drug treatment for reduced levels | <40 mg/dL(<1.0 mmol/L) or drug treatment for reduced levels | <35 mg/dL (0.9 mmol/L) |
Women | <50 mg/dL (<1.3 mmol/L) or drug treatment for reduced levels | <50 mg/dL (<1.3 mmol/L) or drug treatment for reduced levels | <50 mg/dL(<1.3 mmol/L) or drug treatment for reduced levels | <39 mg/dL (1.0 mmol/L) |
Blood Pressure | ≥130/≥85 mmHg or drug treatment for HTN | ≥130/≥85 mmHg or drug treatment for HTN | ≥130/≥85 mmHg or drug treatment for HTN | ≥140/≥90 mmHg |
Fasting Glucose | ≥110 mg/dL (≥6.11 mmol/L) or drug treatment for DM | ≥100 mg/dL (≥5.6 mmol/L) or drug treatment for DM | ≥100 mg/dL (≥5.6 mmol/L) or drug treatment for DM | IGT, IFG, or type 2 DM |
Microalbuminuria | >30 mg albumin/g creatinine |
DM: diabetes mellitus
HDL: high-density lipoprotein cholesterol
HTN: hypertension
IGT: impaired glucose tolerance (2-hour postprandial glucose 140-199 mg/dL (7.8-11.1 mmol/L))
IFG: impaired fasting glucose (fasting glucose 100-126 mg/dL (5.6-7 mmol/L))
IR: insulin resistance