Patient Characteristics.
| Characteristic | Number of Patients |
|---|---|
| Patients enrolled | 10 |
| Age, years Median Range |
72 61-80 |
| Race Caucasian |
10 |
| ECOG PS 0 1 |
3 7 |
| Treatment of the primary Radical prostatectomy Radiation therapy None |
6 1 3 |
| Gleason sum at diagnosis ≤6 7 ≥8 |
1 5 4 |
| Clinical stage at diagnosis (n = 4) T1c T2b T2c M1 Pathological stage (n = 6) T2 T3 N0 N1 |
1 1 2 2 3 3 3 3 |
| Sites of metastatic disease Bone only Lymph nodes only Liver and bone Number with measurable disease |
7 2 1 3 |
| Lesion that could be biopsied | 3 |
| PSA, ng/ml Median Range |
25.86 4.13-2502.75 |
| Hemoglobin, g/dl Median Range |
12.75 10.3-15.1 |
| Alkaline phosphatase, U/L Median Range |
76.5 31-568 |
| Prior therapies Docetaxel for castration sensitive disease Abiraterone Enzalutamide Sipuleucel-T |
1 5 10 1 |
| Number of weeks on enzalutamide prior to study Median Range |
52 29-230 |
| Using narcotics at baseline | 6 |
ECOG PS – Eastern Cooperative Oncology Group Performance Status