Table 1. Sequencing metrics.

Sequence Type	Metric	SC_9008		SC_9009		SC_9010
		Broad	UM	Broad	UM	Broad	UM
WES (somatic)
	MTC	177.99	264.10	147.09	271.13	122.57	265.04
	Selected bases (%)	0.83	0.75	0.84	0.76	0.85	0.72
	Zero coverage targets (%)	0.014	0.018	0.015	0.019	0.015	0.017
	NSV	852	1203	42	57	47	90
	Point Mutations	652	811	38	47	45	82
	Insertion/Deletions	200	392	4	10	2	8
WES (germline)
	MTC	143.40	226.97	173.84	236.99	122.57	188.19
	Selected bases (%)	0.85	0.79	0.86	0.81	0.85	0.75
	Zero coverage targets (%)	0.014	0.020	0.013	0.021	0.015	0.020
	ACMG 56 gene coverage > 30X (%)	100	100	100	100	100	100
RNAseq (somatic)
	Aligned in pairs reads (%)	0.976	0.912	0.973	0.914	0.974	0.920
	PF reads aligned (%)	0.938	0.821	0.948	0.819	0.940	0.812

MTC, mean target coverage; NSV, non-synonymous nucleotide variant.