Figure 4.
A. Reduction of asymmetrical dimethylation of arginine 2 of histone 3 after PRMT6 knockdown in PC-3 cell line; B. Relative expression of methyltransferases that catalyze H3K4me3 in PC3 PRMT6-silenced cells namely MLL complex genes and SMYD3; C. Western blot analysis of H3K4me3 expression after PRMT6 knockdown in PC-3 cells; D. MYC transcript levels in PC-3 PRMT6 silenced cells. *p<0.05 (Mann-Whitney U-test).