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. 2016 Jun 15;7(33):53018–53028. doi: 10.18632/oncotarget.10061

Figure 4.

Figure 4

A. Reduction of asymmetrical dimethylation of arginine 2 of histone 3 after PRMT6 knockdown in PC-3 cell line; B. Relative expression of methyltransferases that catalyze H3K4me3 in PC3 PRMT6-silenced cells namely MLL complex genes and SMYD3; C. Western blot analysis of H3K4me3 expression after PRMT6 knockdown in PC-3 cells; D. MYC transcript levels in PC-3 PRMT6 silenced cells. *p<0.05 (Mann-Whitney U-test).