Figure 7. The combination of sertraline and docetaxel reduces the frequency of proliferating cells and increases that of apoptotic cells to a greater extent than either drug alone.

Tumors from mice administered the vehicle, sertraline, docetaxel, or the combination of each drug were sectioned and these were stained with H&E, antibodies to Ki67 or assayed for fragmented DNA using the TUNEL assay. The scale bars represent 50 μm.