Table 1. Baseline characteristics of patients in three miRNA assessment sets from TCGA.
| Training set | Validation set | Independent set | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Numbers of patients | Low risk | High risk | Numbers of patients | Low risk (%) | High risk (%) | Numbers of patients | Low risk (%) | High risk (%) | |
| Age | |||||||||
| ≤60 year | 40 | 14(35%) | 26(65%) | 54 | 24(44%) | 30(56%) | 57 | 29(51%) | 28(49%) |
| >60 year | 49 | 29(59%) | 20(41%) | 48 | 20(42%) | 28(58%) | 52 | 26(50%) | 26(50%) |
| Gender | |||||||||
| Male | 50 | 20(40%) | 30(60%) | 50 | 26(52%) | 24(48%) | 55 | 19(35%) | 36(65%) |
| Female | 39 | 20(51%) | 19(49%) | 52 | 22(42%) | 30(58%) | 54 | 36(67%) | 18(33%) |
| Karnofsky score | |||||||||
| ≤70 score | 70 | 33(47%) | 37(53%) | 72 | 34(47%) | 38(53%) | 84 | 45(54%) | 39(46%) |
| ≥80 score | 19 | 7(37%) | 12(63%) | 30 | 12(40%) | 18(60%) | 25 | 10(40%) | 15(60%) |
| Tumorlocation | |||||||||
| Fronto lobe or temporal lobe | 40 | 19(48%) | 21(53%) | 48 | 23(48%) | 25(52%) | 52 | 25(48%) | 27(52%) |
| Other lobe* | 49 | 19(39%) | 30(61%) | 54 | 25(46%) | 29(54%) | 57 | 30(53%) | 27(47%) |
| Recurrence | |||||||||
| Yes | 69 | 32(46%) | 37(54%) | 17 | 7(41%) | 10(59%) | 93 | 41(44%) | 53(56%) |
| No | 20 | 8(40%) | 12(60%) | 85 | 41(48%) | 44(52%) | 16 | 9(60%) | 6(40%) |
| MGMT methylight | |||||||||
| methylated | 47 | 22(47%) | 25(53%) | 69 | 38(55%) | 31(45%) | 78 | 42(54%) | 36(46%) |
| unmethylated | 42 | 18(43%) | 24(57%) | 33 | 10(30%) | 23(70%) | 31 | 13(42&) | 18(58%) |
| IDH1 mutant | |||||||||
| mutated | 11 | 5(46%) | 6(54%) | 17 | 9(53%) | 6(47%) | 15 | 9(60%) | 6(40%) |
| unmutated | 78 | 38(49%) | 40(51%) | 85 | 36(42%) | 49(58%) | 94 | 43(46%) | 51(54%) |
| Smoking | |||||||||
| Yes | 60 | 29(48%) | 31(52%) | 49 | 22(45%) | 27(55%) | 77 | 38(49%) | 39(51%) |
| No | 29 | 11(38%) | 18(62%) | 53 | 26(49%) | 27(51%) | 32 | 15(47%) | 17(53%) |
| Family history of cancer† | |||||||||
| Yes | 68 | 30(44%) | 38(56%) | 69 | 30(43%) | 39(57%) | 88 | 43(49%) | 45(51%) |
| No | 21 | 10(48%) | 11(52%) | 33 | 18(55%) | 15(45%) | 21 | 12(57%) | 9(43%) |
*
Other lobe including insular lobe,parietal lobe,cerebellar,lateral ventricles,fourth ventricle, occipital lobe and multiple lobes
†
Family history of cancer means any type tumor suffered in any family menbers.