Figure 1. A HIF-1α sub-signature regulating cell motility acts as an AML-M5 class predictor.
A list of 28 genes that recognize 72% of M5 samples was selected among HIF-1α target genes using PAM algorithm A. Ranked list of the genes used in the classification. B. Multidimensional scaling on 195 AML samples using the signature obtained by the PAM classifier (M5 samples in light gray, non-M5 samples in black).