Table 4. Expression of glutamine metabolism-related proteins in follicular neoplasms.
| Parameters | Total N=264 (%) |
FA n=152 (%) |
FC n=112 (%) |
p-value |
|---|---|---|---|---|
| GLS1 (T) | 0.021 | |||
| Negative | 185 (70.1) | 115 (75.7) | 70 (62.5) | |
| Positive | 79 (29.9) | 37 (24.3) | 42 (37.5) | |
| GDH (T) | 0.001 | |||
| Negative | 144 (54.5) | 96 (63.2) | 48 (42.9) | |
| Positive | 120 (45.5) | 56 (36.8) | 64 (57.1) | |
| ASCT2 (T) | 0.156 | |||
| Negative | 249 (94.3) | 146 (96.1) | 103 (92.0) | |
| Positive | 15 (5.7) | 6 (3.9) | 9 (8.0) |
FA; follicular adenoma, FC: follicular carcinoma, GLS1; glutaminase 1, GDH; glutamate dehydrogenase, ASCT2; amino acid transporter-2