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. 2016 Jul 18;7(33):53628–53641. doi: 10.18632/oncotarget.10682

Table 5. Expression of glutamine metabolism-related proteins according to the histologic subtype of follicular carcinoma (FC).

Parameters Total
N=112 (%)
FC, minimally invasive type
n=99 (%)
FC, widely invasive type
n=13 (%)
p-value
GLS1 (T) 0.493
 Negative 70 (62.5) 63 (63.6) 7 (53.8)
 Positive 42 (37.5) 36 (36.4) 6 (46.2)
GDH (T) 0.394
 Negative 48 (42.9) 41 (41.4) 7 (53.8)
 Positive 64 (57.1) 58 (58.6) 6 (46.2)
ASCT2 (T) 0.257
 Negative 103 (92.0) 90 (90.9) 13 (100.0)
 Positive 9 (8.0) 9 (9.1) 0 (0.0)

FC: follicular carcinoma, GLS1; glutaminase 1, GDH; glutamate dehydrogenase, ASCT2; amino acid transporter-2