Table 7. Multivariate analysis of factors influencing survival of patients with thyroid cancer *.
| Included parameters | Disease-free survival | Overall survival | ||||
|---|---|---|---|---|---|---|
| Hazard ratio | 95% CI | P-value | Hazard ratio | 95% CI | P-value | |
| Age (years) | 0.631 | 0.003 | ||||
| <45 versus ≥45 | 1.263 | 0.488-3.272 | 25.26 | 3.047-209.4 | ||
| Sex | 0.668 | 0.402 | ||||
| Male versus Female | 1.265 | 0.433-3.690 | 1.564 | 0.550-4.449 | ||
| Tumor size (cm) | 0.798 | 0.402 | ||||
| ≤2.0 versus >2.0 | 1.147 | 0.400-3.288 | 1.564 | 0.550-4.449 | ||
| Tumor extension | 0.352 | 0.504 | ||||
| Intrathyroidal versus Extrathyroidal | 0.631 | 0.239-1.663 | 0.688 | 0.229-2.061 | ||
| LN metastasis | 0.019 | 0.014 | ||||
| No versus Yes | 6.021 | 1.352-26.82 | 4.466 | 1.352-14.76 | ||
| GLS1 (T) | 0.273 | 0.422 | ||||
| Negative versus positive | 0.587 | 0.226-1.522 | 0.676 | 0.261-1.757 | ||
| GDH (S) | n/a | 0.009 | ||||
| Negative versus positive | n/a | n/a | 21.48 | 2.178-211.8 | ||
*
cases of AC were excluded. GLS1; glutaminase 1, GDH; glutamate dehydrogenase