Table 1. Characteristics of patients with rectal cancer, SEER 1988-2012.
| All Patients | Stage I-III | Stage IV | |
|---|---|---|---|
| Characteristic | N = 105,511 | N = 88,491 | N = 17,020 |
| Sex | |||
| Male | 61693 (58.5%) | 51252 (57.9%) | 10441 (61.3%) |
| Female | 43818 (41.5%) | 37239 (42.1%) | 6579 (38.7%) |
| Age, years | |||
| Median (interquartile range) | 66 (56-76) | 67 (56-76) | 64 (54-74) |
| 18-44 | 6903 (6.5%) | 5438 (6.1%) | 1465 (8.6%) |
| 45-54 | 16786 (15.9%) | 13697 (15.5%) | 3089 (18.1%) |
| 55-64 | 24570 (23.3%) | 20329 (23.0%) | 4241 (24.9%) |
| 65-74 | 27720 (26.3%) | 23542 (26.6%) | 4178 (24.6%) |
| 75 and older | 29532 (28.0%) | 25485 (28.8%) | 4047 (23.8%) |
| Ethnicity/Race | |||
| White | 78593 (74.5%) | 66574 (75.2%) | 12019 (70.6%) |
| African American | 8473 (8.0%) | 6725 (7.6%) | 1748 (10.3%) |
| Asian | 8403 (8.0%) | 7056 (8.0%) | 1347 (7.9%) |
| Hispanic | 9388 (8.9%) | 7629 (8.6%) | 1759 (10.3%) |
| Native American | 654 (0.6%) | 507 (0.6%) | 147 (0.9%) |
| Histology | |||
| Non-mucinous Adenocarcinoma | 94735 (89.8%) | 79875 (90.3%) | 14860 (87.3%) |
| Mucinous Adenocarcinoma | 6512 (6.2%) | 5443 (6.1%) | 1069 (6.3%) |
| Other | 4264 (4.0%) | 3173 (3.6%) | 1091 (6.4%) |
| Differentiation | |||
| Good | 8456 (8.0%) | 7642 (8.6%) | 814 (4.8%) |
| Moderate | 67967 (64.4%) | 58791 (66.5%) | 9176 (53.9%) |
| Poor | 16509 (15.7%) | 12687 (14.3%) | 3822 (22.5%) |
| Not determined | 12579 (11.9%) | 9371 (10.6%) | 3208 (18.8%) |
| Lymph Nodes Examined | |||
| <12 nodes | 71544 (67.8%) | 58369 (66.0%) | 13175 (77.4%) |
| ≥12 nodes | 31333 (29.7%) | 28138 (31.8%) | 3195 (18.8%) |
| Unknown | 2634 (2.5%) | 1984 (2.2%) | 650 (3.8%) |
| Surgery1 | |||
| Not cancer-directed | 18483 (17.5%) | 9084 (10.3%) | 9399 (55.2%) |
| Local | 13775 (13.1%) | 13251 (15.0%) | 524 (3.1%) |
| Radical | 71280 (67.5%) | 64493 (72.8%) | 6787 (39.9%) |
| Unknown | 1973 (1.9%) | 1663 (1.9%) | 310 (1.8%) |
| Radiation Sequence with Surgery1,2 | |||
| Neoadjuvant | 23020 (53.7%) | 21167 (53.5%) | 1853 (55.5%) |
| Adjuvant | 18578 (43.3%) | 17239 (43.6%) | 1339 (40.1%) |
| Other sequence3 | 1291 (3.0%) | 1146 (2.9%) | 145 (4.4%) |
| Chemotherapy4 | |||
| No/unknown | 50377 (47.7%) | 44719 (50.5%) | 5658 (33.2%) |
| Any | 55134 (52.3%) | 43772 (49.5%) | 11362 (66.8%) |
| Year of Diagnosis | |||
| 1988-2003 | 51171 (48.5%) | 43506 (49.2%) | 7665 (45.0%) |
| 2004-2012 | 54340 (51.5%) | 44985 (50.8%) | 9355 (55.0%) |
1
Initial surgical procedure
2
Patients who received both initial radiation and local or radical surgery were included
3
Includes radiation both before and after surgery; intraoperative radiation +/- other radiation given before or after surgery; sequence unknown, but both surgery and radiation were performed
4
First course