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. 2016 Jul 20;7(33):53679–53701. doi: 10.18632/oncotarget.10725

Figure 2. The expression of HO-1 is strongly correlated with IK6.

Figure 2

Figure 2

Figure 2

A. Differential expression of HO-1 mRNA in adult BCR-ABL1-positive B-ALL patients and normal CD34+ cells were determined by qRT-PCR. B. Western blot analysis of Ikaros expression in IK6-positive and –negative patients. C, D. Western blot analysis of HO-1 expression at protein level in adult BCR-ABL1-positive B-ALL patients and normal CD34+ cells. E. Scatterplot representation of the correlation between the expression of HO-1 and Ikaros in patient samples. F. Co-immunoprecipitation assay to verify the interaction of Flag-IK6 with Myc-HO-1 in SupB15 cells (upper panel) and the endogenous interaction of Ikaros with HO-1 in primary leukemic cells (lower panel). (Pts=patients).