Skip to main content
. 2016 Jul 22;7(33):53837–53852. doi: 10.18632/oncotarget.10782

Figure 1. Results of glucose and glutamine consumption examinations.

Figure 1

As shown in A., the LNCaP PDHA1 KO cells consume 5.33mg while the parental cells consume only about 2.13mg glucose after 12hrs culture, which show a significant difference with a P value less than 0.001. At 24h culture the LNCaP PDHA1 KO cells consume 3.51mgwhile the parental cells consume about 7.45mg glucose (P <0.001). The data are normalized based on cell number in each experiment. Similarly, B. shows the results of glutamine consumption. At 24hrs culture the LNCaP PDHA1 KO cells consume 3.22μmol while the LNCaP parental cells consume only about 1.52μmol L-glutamine, which show a significant difference with a P value less than 0.001. At 48hrs culture the LNCaP PDHA1 KO cells consume 4.01μmol in the medium while the LNCaP parental cells consume about 1.81μmol L-glutamine (P=0.000). The uneven cell numbers caused by different division ratio after 24hrs and 48hrs's cultivation were normalized. ***P<0.001.