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. Author manuscript; available in PMC: 2017 Feb 2.
Published in final edited form as: J Neural Transm (Vienna). 2016 Oct 21;124(2):185–192. doi: 10.1007/s00702-016-1635-1

Table 3.

Frequency of spatial patterns (R = random distribution, reg = regular or uniform distribution, reg clusters = regularly distributed clusters of inclusions) of the tau-immunoreactive neurofibrillary tangles (NFT) and neuritic plaques (NP) in the cerebral cortex and hippocampus in seven cases of Alzheimer’s disease neuropathologic change (ADNC) without CTE

Pathology Region R Reg Reg clusters Large
clusters
NFT Cortex 1 0 22 (12) 7
Sub/HC/DG 3 0 9 (0) 1
NP Cortex 1 1 12 (8) 12
Sub/HC/DG 3 1 11 (0) 5

Figures in parentheses in column 5 indicate percentage of regions investigated in which cluster size was in the range 400–800 µm

Chi-square (χ2) contingency tests: CTE vs ADNC NFT χ2 = 19.29 (3DF, P > 0.001) and NP χ2 = 9.80 (3DF, P < 0.05)