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In vivo CT-guided bacteriolytic therapy in PC3 tumor-bearing mouse model. (a) In vivo CT-guided placement of injection-catheter, (b) In vivo CT images of PC3 tumor following intra-tumoral injection of BGNP-coated C. novyi-NT spores (injection-catheter removed), and (c) 3D-rendered CT images of mouse following injection of BGNP-coated C. novyi-NT spores (Yellow arrow indicates hyper-attenuated region due to deposition of the BGNP-coated spores).
