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Icariside II improved Aβ25-35-induced neuronal apoptosis in the hippocampus. (A–D) TUNEL staining of hippocampus CA1 region sections (magnification 400×, scale bar 50 μm) and (E) quantitative analysis of apoptotic cells in the hippocampus CA1 region. Data were expressed as mean ± SEM, n = 4. ∗∗P < 0.01 vs. sham; ##P < 0.01 vs. Aβ alone.
