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. 2017 Feb 2;8:57. doi: 10.3389/fimmu.2017.00057

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Copyright © 2017 Albarracin, Kobayashi, Iida, Sato, Nochi, Aso, Salva, Alvarez, Kitazawa and Villena.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of type I interferons (IFN-β and IFN-α), IFN regulatory factor 3, and IFN-induced antiviral genes in porcine intestinal epithelial (PIE) cells treated with immunobiotic Lactobacillus rhamnosus CRL1505 or Lactobacillus plantarum CRL1506 and challenged with the viral molecular associated pattern poly(I:C), analyzed by quantitative PCR. Non-lactobacilli-treated PIE cells with or without poly(I:C) challenge were used as controls. The results represent data from three independent experiments. Asterisks indicate significant differences when compared to poly(I:C)-challenged control PIE cells (*P < 0.05, **P < 0.01).