Table 4.
Tumor characteristics in total and within Volpara Density Grade (VDG) categories (based on the available views)
| Total | VDG 1 | VDG 2 | VDG 3 | VDG 4 | p trend | ||
|---|---|---|---|---|---|---|---|
| Proportion invasive tumorsa | |||||||
| Total (N = 898) | Invasive [N (%)] | 757 (84.3%) | 90 (80.4%) | 333 (87.2%) | 254 (83.6%) | 80 (80.0%) | 0.49 |
| Screen-detected cancer (N = 665) | Invasive [N (%)] | 529 (79.5%) | 75 (78.1%) | 250 (84.2%) | 163 (77.3%) | 41 (67.2%) | 0.03 |
| Interval cancer (N = 233) | Invasive [N (%)] | 228 (97.9%) | 15 (93.8%) | 83 (97.6%) | 91 (97.8%) | 39 (100.0%) | 0.20 |
| pT (only invasive tumors)b | |||||||
| Total (N = 700) | T1 [N (%)] | 503 (71.9%) | 70 (81.4%) | 231 (73.6%) | 153 (66.8%) | 49 (69.0%) | |
| T2 [N (%)] | 171 (24.4%) | 15 (17.4%) | 74 (23.6%) | 65 (28.4%) | 17 (23.9%) | 0.02c | |
| T3 & T4 [N (%)] | 26 (3.7%) | 1 (91.2%) | 9 (2.9%) | 11 (4.8%) | 5 (7.0%) | ||
| Screen-detected cancer (N = 511) | T1 [N (%)] | 404 (79.1%) | 63 (85.1%) | 195 (79.6%) | 116 (75.8%) | 30 (76.9%) | |
| T2 [N (%)] | 97 (19.0%) | 11 (14.9%) | 46 (18.8%) | 33 (21.6%) | 7 (17.9%) | 0.14c | |
| T3 & T4 [N (%)] | 10 (2.0%) | 0 (0.0%) | 4 (1.6%) | 4 (2.6%) | 2 (5.1%) | ||
| Interval cancer (N = 189) | T1 [N (%)] | 99 (52.4%) | 7 (58.3%) | 36 (52.2%) | 37 (48.7%) | 19 (59.4%) | |
| T2 [N (%)] | 74 (39.2%) | 4 (33.3%) | 28 (40.6%) | 32 (42.1%) | 10 (31.3%) | 0.87c | |
| T3 and T4 [N (%)] | 16 (8.5%) | 1 (8.3%) | 5 (7.2%) | 7 (9.2%) | 3 (9.4%) | ||
| Lymph node status (only invasive tumors)d | |||||||
| Total (N = 741) | Positive [N (%)] | 234 (31.6%) | 18 (20.2%) | 105 (32.3%) | 87 (35.2%) | 24 (30.0%) | 0.12 |
| Screen-detected cancer (N = 518) | Positive [N (%)] | 152 (29.3%) | 13 (17.6%) | 75 (30.7%) | 51 (32.1%) | 13 (31.7%) | 0.08 |
| Interval cancer (N = 223) | Positive [N (%)] | 82 (36.8%) | 5 (33.3%) | 30 (37.0%) | 36 (40.9%) | 11 (28.2%) | 0.68 |
| Tumor diameter (only invasive tumors)e | |||||||
| Total (N = 691) | Median (mm) (IQR) | 15 (10; 22) | 12 (8; 18) | 15 (10; 21) | 17 (11; 25) | 14 (10; 22) | 0.01 |
| Screen-detected cancer (N = 500) | Median (mm) (IQR) | 13 (9; 19) | 11 (8; 17) | 13 (10; 19) | 14 (10; 20) | 12 (8; 19) | 0.10 |
| Interval cancer (N = 191) | Median (mm) (IQR) | 20 (14; 30) | 20 (13; 33) | 19 (16; 30) | 21 (16; 31) | 16 (12; 25) | 0.34 |
aInformation on invasiveness is missing for 3 tumors (2 screen-detected and 1 interval tumors)
bInformation on pT status is missing for 57 tumors (18 screen-detected and 39 interval tumors)
c p-trend determined for T1 versus T2, T3, and T4
dInformation on lymph node status is missing for 16 tumors (11 screen-detected and 5 interval tumors)
eInformation on tumor diameter is missing for 66 tumors (29 screen-detected and 37 interval tumors)