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. 2016 Sep 1;62(1):3–13. doi: 10.1007/s00038-016-0884-y

Table 3.

Direct healthcare costs associated to lifestyle-related risk factors

Chronic diseases Direct healthcare costs (CAN $2010) Risk factors (RF) Adj. PAFa (%) Costs attributable to risk factors ($) Total costs adjusted for multiple exposition ($)
(1) Pulmonary diseases
 Chronic Obstructive Pulmonary disease $394,736,365 Smoking 49.52 $195,464,225 $221,658,019
Insufficient consumption of fruits and vegetables 13.14 $51,887,048
 Asthma $335,893,285 Smoking 9.88 $33,195,061 $77,751,443
Obesity and overweight 14.72 $49,442,607
(2) Cancers
 Lung cancers $151,601,720 Smoking 70.56 $106,973,175 $111,056,160
Insufficient consumption of fruits and vegetables 9.15 $13,869,767
 Breast cancers $77,422,929 Physical inactivity 4.55 $3,520,702 $21,058,496
Insufficient consumption of fruits and vegetables 23.73 $18,373,294
 Post-menopausal breast cancers $61,164,114 Obesity and overweight 4.29 $2,621,537 $2,621,537
 Colon and rectum cancers $131,935,455 Obesity and overweight 22.71 $29,963,004 $47,049,393
Physical inactivity 16.76 $22,106,957
(3) Cardiovascular diseases
 Stroke $457,390,301 Smoking 16.48 $75,356,930 $161,321,080
Insufficient consumption of fruits and vegetables 6.17 $28,230,351
Physical inactivity 12.48 $57,064,937
Obesity and overweight 5.63 $25,751,457
 Ischemic heart diseases $963,691,242 Smoking 23.55 $226,961,558 $522,497,040
Insufficient consumption of fruits and vegetables 8.57 $82,558,945
Physical inactivity 9.67 $93,144,537
Obesity and overweight 27.50 $264,972,860
 Hypertension $968,824,255 Smoking 6.25 $60,584,638 $436,253,706
Insufficient consumption of fruits and vegetables 22.24 $215,504,459
Obesity and overweight 24.59 $238,211,364
(4) Metabolic disease
 Type II diabetes $379,683,944 Insufficient consumption of fruits and vegetables 1.89 $7,161,712 $258,622,744
Physical inactivity 10.85 $41,212,151
Obesity and overweight 63.55 $241,271,621
(5) Musculoskeletal diseases
 Osteoarthritis $238,593,747 Obesity and overweight 41.21 $98,326,933 $98,326,933
 Direct costs of chronic diseases $4,160,937,358 Total costs attributable to risk factors $1,958,216,550

Canada 2016

aPopulation attributable fraction