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CAB39 is the potential target gene of miR-451. (a) The target sites for miR-451 in the 3′UTR of CAB39 and the mutant target sites. (b) The EGFP Fluorescence Reporter result of PANC-1 cells cotransfected with CAB39-3′UTR/CAB-3′UTR-mutor miR-451/anti-miR-451 or miR-NC/anti-miR-NC. The expression levels of CAB39 mRNA in PANC-1 cells transfected with miR-451/anti-miR-451 or miR-NC/anti-miR-NC level determined by qRT-PCR (c) and Western blot (d); ∗∗P < 0.01 and ∗∗∗P < 0.001.
