Table 1.

Univariable binary regression of circadian risk development for binary output variables. Shown are the results of univariable regression analyses of the circadian risk development per 3-hour day and night shift intervals for the investigated endpoints hospital discharge on dialysis [Yes/No], delayed graft function [Yes/No], early postoperative graft loss [Yes/No], postoperative graft loss due to surgical reasons [Yes/No], and reoperation [Yes/No]. Values of calculated odds ratios of each time interval were plotted on radar-plots to visualize the circadian risk developments of each investigated endpoint.

	3 h interval	No	Yes	%	Univariable binary regression			χ 2	Circadian risk development
		n = 1044	n = 218		p	OR	95% CI
Reoperation	12 AM–3 AM (n = 96)	81	15	15.6	0.657	0.878	0.496–1.555	0.653
	3 AM–6 AM (n = 25)	17	8	32	0.056	2.301	0.980–5.402	0.070
	6 AM–9 AM (n = 134)	117	17	12.7	0.140	0.670	0.394–1.140	0.124
	9 AM–12 PM (n = 267)	229	38	14.2	0.140	0.751	0.514–1.098	0.131
	12 AM–3 PM (n = 274)	226	48	17.5	0.904	1.022	0.718–1.454	0.904
	3 PM–6 PM (n = 169)	136	33	19.5	0.406	1.191	0.789–1.798	0.412
	6 PM–9 PM (n = 157)	133	24	15.3	0.482	0.847	0.534–1.344	0.475
	9 PM–12 AM (n = 140)	105	35	25.0	0.011	1.710	1.131–2.588	0.014
	3 h interval	No	Yes	%	Univariable binary regression			χ 2	Circadian risk development
		n = 1207	n = 55		p	OR	95% CI
Perioperative graft loss	12 AM–3 AM (n = 96)	94	2	2.1	0.269	0.447	0.107–1.862	0.211
	3 AM–6 AM (n = 25)	21	4	16.0	0.008	4.430	1.467–13.38	0.024
	6 AM–9 AM (n = 134)	129	5	3.7	0.707	0.836	0.327–2.133	0.701
	9 AM–12 PM (n = 267)	259	8	3.0	0.224	0.623	0.291–1.335	0.200
	12 PM–3 PM (n = 274)	262	12	4.4	0.984	1.007	0.523–1.937	0.984
	3 PM–6 PM (n = 169)	159	10	5.9	0.289	1.465	0.724–2.965	0.307
	6 PM–9 PM (n = 157)	151	6	3.8	0.725	0.856	0.361–2.033	0.720
	9 PM–12 AM (n = 140)	132	8	5.7	0.407	1.386	0.641–2.997	0.423
	3 h interval	No	Yes	%	Univariable binary regression			χ 2	Circadian risk development
		n = 1241	n = 21		p	OR	95% CI
Perioperative graft loss due to surgical reasons	12 AM–3 AM (n = 96)	95	1	1	0.616	0.597	0.079–4.496	0.588
	3 AM–6 AM (n = 25)	22	3	12	0.001	9.242	2.537–33.67	0.007
	6 AM–9 AM (n = 134)	131	3	2.2	0.583	1.413	0.411–4.863	0.598
	9 AM–12 PM (n = 267)	265	2	0.7	0.205	0.388	0.090–1.677	0.151
	12 PM–3 PM (n = 274)	269	5	1.8	0.813	1.130	0.410–3.113	0.815
	3 PM–6 PM (n = 169)	166	3	1.8	0.902	1.080	0.315–3.708	0.903
	6 PM–9 PM (n = 157)	157	0	0	0.996	0.000	0.000	0.018
	9 PM–12 AM (n = 140)	136	4	2.9	0.249	1.913	0.635–5.769	0.281
	3 h interval	No	Yes	%	Univariable binary regression			χ 2	Circadian risk development
		n = 601	n = 261		p	OR	95% CI
Delayed graft function	12 AM–3 AM (n = 73)	48	25	34.2	0.441	1.220	0.735–2.026	0.445
	3 AM–6 AM (n = 15)	12	3	20.0	0.388	0.571	0.160–2.040	0.364
	6 AM–9 AM (n = 99)	68	31	31.3	0.812	1.056	0.672–1.660	0.812
	9 AM–12 PM (n = 186)	137	49	26.3	0.188	0.783	0.544–1.127	0.183
	12 PM–3 PM (n = 181)	121	60	33.1	0.345	1.184	0.834–1.681	0.347
	3 PM–6 PM (n = 112)	82	30	26.8	0.389	0.822	0.526–1.284	0.384
	6 PM–9 PM (n = 105)	76	29	27.6	0.527	0.863	0.548–1.361	0.524
	9 PM–12 AM (n = 91)	57	34	37.4	0.121	1.429	0.910–2.246	0.126
	3 h interval	No	Yes	%	Univariable binary regression			χ 2	Circadian risk development
		n = 862	n = 102		p	OR	95% CI
Discharge on dialysis	12 AM–3 AM (n = 77)	73	4	5.1	0.119	0.441	0.158–1.233	0.081
	3 AM–6 AM (n = 19)	15	4	21.1	0.145	2.305	0.750–7.082	0.178
	6 AM–9 AM (n = 114)	99	15	13.2	0.342	1.329	0.739–2.389	0.354
	9 AM–12 PM (n = 207)	186	21	10.1	0.818	0.942	0.568–1.564	0.817
	12 PM–3 PM (n = 200)	181	19	9.5	0.577	0.861	0.510–1.456	0.572
	3 PM–6 PM (n = 127)	112	15	11.8	0.629	1.155	0.645–2.068	0.633
	6 PM–9 PM (n = 114)	105	9	7.9	0.323	0.698	0.342–1.425	0.303
	9 PM–12 AM (n = 106)	91	15	14.2	0.208	1.461	0.810–2.634	0.223