Table 1. Summary of PDT effects on CT26 tumours.
| Animal number | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Photobleaching, % | 75 | 80 | 77 | 73 | 74 | 77 | 57 | 74 | 76 | 71 | 62 |
| Disappearance time on MML-OCA (hrs) | 0 | 0 | 0 | 6 | 6 | 24 | 24 | 24 | 24 | — | — |
| Microvascular damage (histology)1 | S | S | S | S | S | S | S | S | S | W | W |
| Viable tumour cells, % (histology) | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 20 | 60 | 85 | 97 |
| TGI, % (tumour volume metric) | 159 | 152 | 165 | 156 | 163 | 147 | 157 | 142 | 135 | 97 | 81 |
aClassified as severe S (>30% of the vessels exhibited vessel wall damage) or weak W (<30% of the vessels exhibited vessel wall damage). See text for details.