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. 2017 Feb 2;7:41539. doi: 10.1038/srep41539

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Copyright © 2017, The Author(s)

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(A) Intracellular pro-IL-1β concentrations (ELISA) in BMDM lysates. BMDM primed with LPS (500 ng/ml) were treated with quercetin, tamoxifen or serum-free medium. (B,C) Wild type and Atg16l1^fl/fl LysM^Cre BMDM primed with LPS (500 ng/ml) were stimulated with (B) ATP (5 mM) or (C) Nigericin (10 μM) and treated with quercetin 30 minutes before secondary stimulation. Data shown are representative of two or more independent experiments (means ± SD) *p < 0.05, ***p < 0.001.