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. 2017 Feb 2;7:41605. doi: 10.1038/srep41605

Figure 5. DMF prevents development of pulmonary fibrosis in bleomycin mouse model.

Figure 5

Lung fibrosis was induced by bleomycin (BLEO) delivered through osmotic pump, PBS was used as a control. Mice were injected daily with 90 mg/kg DMF or vehicle (VEH) for 4 weeks. (A) Representative pictures of lung sections stained with Gomori trichrome for collagen (blue). n = 3–5 mice per group. (B) Quantification of blue area in Gomori trichrome staining expressed as percentage of the total tissue area. (C,D) Gene expression measured by qPCR in a whole lung tissue. *P < 0.05, **P < 0.01, ***P < 0.001.