FIGURE 1.

(A and B) Time–activity curves for HC and AD subjects, respectively. PET data are represented by ●, solid line is SRTM fit to the data, dashed line is SRTM2 fit. (C) SUVR for single HC subject shown in A, and mean ± SD of all HC subjects (solid/dotted lines). (D) SUVRs for AD subject shown in B and mean ± SD of all AD subjects in (solid/dotted lines). Circles represent single subject SUVR, solid line is mean across subject groups, and dashed line represents SD of subject group. Putamen represents off-target binding with quantification challenges.