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. 2016 Dec 19;6(1):46–56. doi: 10.1002/open.201600141

Figure 2.

Figure 2

Secondary‐structure arrangements of full‐length DNAzymes: A) Dz15 and B) Dz27. In the structures, the DMS‐modified cytosine residues are marked by blue circles and S1 nuclease digestion sites are denoted by red arrows. The sites at which the sequences were truncated are denoted by black triangles. Secondary‐structure models of the shortened DNAzymes: C) Dz15WS and D) Dz27WS were predicted by using the RNAstructure 5.6 program. Green letters mark the initially randomized region of DNAzymes and the catalytic cleavage site is marked as rA in red.