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. 2016 Dec 19;6(1):46–56. doi: 10.1002/open.201600141

Figure 6.

Figure 6

Effect of RNA base identity at the cleavage position on the reaction efficiency of trans‐acting DNAzymes: A) Dz15WS_E and B) Dz27WS_E. The oligonucleotide substrates were synthesized with adenosine (rA), guanosine (rG), cytidine (rC), or uridine (rU) at the cleavage site. All mutated nucleotides are denoted by a double underline. Cleavage reactions were performed in sodium citrate buffer pH 2.5–5.0 at 37 °C for 3 h.