TABLE 1.
Details for species with high correlations with the three variablesf
| Variable and no.a | Phylum | Species | HOTb |
|---|---|---|---|
| Positive | |||
| pH | |||
| S40 | Bacteroidetes | Capnocytophaga sp. | 332 |
| S269e | Bacteroidetes | Prevotella multisaccharivorax | 794 |
| S227 | Bacteroidetes | Prevotella oralis | 705 |
| S45 | Bacteroidetes | Alloprevotella sp. | 912 |
| S382e | Firmicutes | Streptococcus sobrinus | 768 |
| S158 | Fusobacteria | Leptotrichia buccalis | 563 |
| S1 | Proteobacteria | Neisseria subflava | 476 |
| S154 | Proteobacteria | Cardiobacterium hominis | 633 |
| S237c | Proteobacteria | Neisseria lactamica | 649 |
| S344 | Spirochaetes | Treponema sp. | 227 |
| S306 | Tenericutes | Mycoplasma faucium | 606 |
| Iron | |||
| S43 | Bacteroidetes | Prevotella sp. | 299 |
| S116 | Bacteroidetes | Prevotella veroralis | 572 |
| S194 | Bacteroidetes | Capnocytophaga sp. | 863 |
| S330e | Firmicutes | Lachnoanaerobaculum sp. | 496 |
| S207 | Firmicutes | Mitsuokella sp. | 521 |
| S218 | Firmicutes | Moryella sp. | 419 |
| S46 | Firmicutes | Streptococcus constellatus | 576 |
| S60d | Firmicutes | Streptococcus sp. | 56 |
| S351 | Proteobacteria | Desulfovibrio sp. | 40 |
| S38 | Spirochaetes | Treponema amylovorum | 541 |
| S123d | Synergistetes | Fretibacterium fastidiosum | 363 |
| DMFT | |||
| S183 | Actinobacteria | Atopobium rimae | 750 |
| S310e | Bacteroidetes | Capnocytophaga sp. | 902 |
| S125 | Bacteroidetes | Prevotella shahii | 795 |
| S234d | Firmicutes | Megasphaera sp. | 123 |
| S181 | Firmicutes | Lachnospiraceae [G-2] sp. | 88 |
| S120d | Firmicutes | Clostridiales [F-1][G-1] sp. | 93 |
| S109 | Firmicutes | Veillonellaceae [G-1] sp. | 155 |
| S54 | Spirochaetes | Treponema denticola | 584 |
| S352e | TM7 | TM7 [G-4] sp. | 355 |
| Negative | |||
| pH | |||
| S141 | Bacteroidetes | Bacteroidetes [G-6] sp. | 516 |
| S98 | Bacteroidetes | Bacteroidetes [G-5] sp. | 505 |
| S14 | Bacteroidetes | Porphyromonas endodontalis | 273 |
| S256 | Bacteroidetes | Bacteroidetes [G-5] sp. | 511 |
| S51 | Bacteroidetes | Prevotella sp. | 526 |
| S108 | Firmicutes | Lachnospiraceae [G-3] sp. | 100 |
| S412 | Firmicutes | Enterococcus saccharolyticus | 802 |
| S189 | Firmicutes | Peptostreptococcaceae [XI][G-4] sp. | 369 |
| S149 | Firmicutes | Lactobacillus vaginalis | 51 |
| S387e | Firmicutes | Enterococcus durans | 880 |
| S241 | Fusobacteria | Leptotrichia sp. | 218 |
| S203 | Fusobacteria | Fusobacterium sp. | 370 |
| S122 | Fusobacteria | Leptotrichiaceae [G-1] sp. | 210 |
| S128 | Proteobacteria | Haemophilus parainfluenzae | 718 |
| S71 | Spirochaetes | Treponema sp. | 235 |
| S200 | Spirochaetes | Treponema sp. | 226 |
| Iron | |||
| S408 | Actinobacteria | Bifidobacterium dentium | 588 |
| S291 | Actinobacteria | Olsenella sp. | 807 |
| S69 | Actinobacteria | Corynebacterium matruchotii | 666 |
| S295 | Actinobacteria | Actinomyces sp. | 897 |
| S276 | Bacteroidetes | Porphyromonas sp. | 275 |
| S68 | Bacteroidetes | Flavobacteriales [G-1] sp. | 318 |
| S40 | Bacteroidetes | Capnocytophaga sp. | 332 |
| S36 | Bacteroidetes | Prevotella denticola | 291 |
| S260 | Firmicutes | Enterococcus italicus | 803 |
| S198 | Firmicutes | Peptostreptococcaceae [XI][G-5] sp. | 493 |
| S375 | Proteobacteria | Ralstonia sp. | 27 |
| S1 | Proteobacteria | Neisseria subflava | 476 |
a
No. indicates the number of the species in the RDA plot (see Fig. S4); boldface font indicates a correlation of >0.996 (±5°).
b
HOT indicates the human oral taxon ID in the Human Oral Microbiome Database (http://www.homd.org/index.php).
c
Non-caries-associated species.
d
Caries-associated species.
e
Low-abundance species with a community-wide impact.
f
Correlation value of >0.985 (±10°) (Fig. 5b).