Fig. 1.
Therapeutic effects of Zn on general changes and renal function in OVE26 type 1 diabetes mouse model. Three-month-old male OVE26 mice and FVB control mice were given Zn (5 mg/kg) or physiological saline every other day for 3 months. (A) Blood glucose, (B) urinary ACR, (C) plasma insulin concentration, (D) kidney size, and (E) kidney weight (KW) to body weight (BW) ratio were measured. Data are presented as the mean ± SD (n = 6). *p < 0.05 vs control (Ctrl); #p < 0.05 vs corresponding DM group.