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. Author manuscript; available in PMC: 2017 Feb 2.
Published in final edited form as: Free Radic Biol Med. 2013 Dec 1;68:22–34. doi: 10.1016/j.freeradbiomed.2013.11.015

Fig. 7.

Fig. 7

Effects of Zn on the expression of renal expression and phosphorylation of Akt downstream effectors and its negative regulators in Akt2-KO diabetic mice. Expression and phosphorylation of (A) GSK-3β and (B) GS, as well as expression of (C) HKII and (D) PGC-1α, were examined by Western blotting. Renal PTEN expression and phosphorylation, along with PTP1B and TRB3 expression, were measured by (E) Western blot. Data are presented as the mean ± SD (n = 6). *p < 0.05 vs control (Ctrl); #p < 0.05 vs Akt2-KO; &p<0.05 vs the Zn supplementation (Zn).