Table 4.
Predictors of leucopenia
| Variables | Leucopenia | COR (95% CI) | P-value | AOR (95% CI) | P-Value | |
|---|---|---|---|---|---|---|
| Yes n (%) | No n (%) | |||||
| Sex | ||||||
| F | 41 (39.4) | 63 (60.6) | 0.98 (0.53–1.84) | 0.970 | ||
| M | 27 (39.7) | 41 (60.3) | 1 | |||
| Age | ||||||
| 18–29 | 23 (38.3) | 37 (61.7) | 1 | |||
| 30–39 | 35 (42.2) | 48 (57.8) | 1.17 (0.59–2.31) | 0.645 | ||
| 40–49 | 7 (30.4) | 16 (69.6) | 0.70 (0.25–1.97) | 0.504 | ||
| ≥ 50 | 3 (50.0) | 3 (50.0) | 1.61 (0.23–8.65) | 0.580 | ||
| HAART status | ||||||
| Yes | 56 (39.4) | 86 (60.6) | 1 | |||
| No | 12 (40.0) | 18 (60.0) | 1.02 (0.46–2.28) | 0.954 | ||
| Opportunistic infection | ||||||
| Yes | 5 (31.2) | 11 (68.8) | 0.67 (0.22–2.02) | 0.479 | ||
| No | 63 (40.4) | 93 (59.6) | 1 | |||
| Malaria infection | ||||||
| Yes | 37 (43.0) | 49 (57.0) | 1.34 (0.73–2.47) | 0.350 | ||
| No | 31 (36.0) | 55 (64.0) | 1 | |||
| Malaria parasitic density (parasite/μl) | ||||||
| 1–999 | 13 (61.9) | 8 (38.1) | 1 | 1 | ||
| 1000–9999 | 20 (46.5) | 23 (53.3) | 0.53 (0.18–1.55) | 0.250 | 0.55 (0.18–1.69) | 0.303 |
| ≥ 10000 | 4 (18.2) | 18 (81.8) | 0.14 (0.34–0.55) | 0.005 | 0.13 (0.03–0.57) | 0.007 |
| CD4 + count (cells/μl) | ||||||
| ≤ 200 | 16 (61.5) | 10 (38.5) | 7.12 (2.58–19.61) | <0.001 | 4.77 (1.23–18.45) | 0.023 |
| 200–499 | 25 (29.8) | 59 (70.2) | 3.11 (1.47–6.57) | 0.003 | 2.85 (0.94–8.62) | 0.064 |
| ≥ 500 | 20 (32.3) | 42 (67.7) | 1 | 1 | ||
*COR-Crude odd ratio, AOR-Adjusted odd ratio, CI-Confidence interval, 1- indicator and statistically significant at p < 0.05