Table 4.

NLR associated single CpG loci median (IQR) beta values in glioma patient subgroups

CpG loci	NLR status			Tumor grade			Mutation status
	NLR high	NLR low	P	II/III	IV	P	IDH1	TERT	P
cg25938803	24.18 (22.72, 26.16)	33.55 (31.25, 39.00)	<0.001	28.33 (24.67, 32.50)	31.40 (26.20, 38.09)	0.1	30.73 (26.13, 34.66)	30.31 (24.44, 35.24)	0.8
cg00901982	20.63 (19.11, 22.61)	30.29 (26.67, 34.76)	<0.001	24.19 (21.17, 26.97)	27.71 (23.16, 34.32)	0.04	26.71 (23.00, 30.73)	24.69 (21.12, 32.06)	0.5
cg01591037	25.48 (23.58, 27.93)	33.87 (32.13, 39.76)	<0.001	30.14 (25.84, 33.75)	32.66 (27.94, 38.44)	0.1	32.01 (27.50, 36.35)	31.03 (25.84, 36.50)	0.6
cg10456459	26.49 (24.34, 28.20)	38.02 (35.68, 43.86)	<0.001	32.19 (27.47, 35.90)	36.44 (27.72, 44.06)	0.05	36.14 (28.20, 39.10)	32.97 (27.36, 39.06)	0.5
cg03621504	20.23 (18.28, 21.37)	26.25 (23.76, 30.42)	<0.001	22.47 (20.74, 26.12)	23.76 (21.39, 29.92)	0.2	23.66 (20.89, 26.40)	22.90 (20.88, 26.56)	0.8

Note: Beta values are represented as percentages (beta values times 100). Median differences between groups were tested using a Mann-Whitney U test