Table 4.
CpG loci | NLR status | Tumor grade | Mutation status | ||||||
---|---|---|---|---|---|---|---|---|---|
NLR high | NLR low | P | II/III | IV | P | IDH1 | TERT | P | |
cg25938803 | 24.18 (22.72, 26.16) | 33.55 (31.25, 39.00) | <0.001 | 28.33 (24.67, 32.50) | 31.40 (26.20, 38.09) | 0.1 | 30.73 (26.13, 34.66) | 30.31 (24.44, 35.24) | 0.8 |
cg00901982 | 20.63 (19.11, 22.61) | 30.29 (26.67, 34.76) | <0.001 | 24.19 (21.17, 26.97) | 27.71 (23.16, 34.32) | 0.04 | 26.71 (23.00, 30.73) | 24.69 (21.12, 32.06) | 0.5 |
cg01591037 | 25.48 (23.58, 27.93) | 33.87 (32.13, 39.76) | <0.001 | 30.14 (25.84, 33.75) | 32.66 (27.94, 38.44) | 0.1 | 32.01 (27.50, 36.35) | 31.03 (25.84, 36.50) | 0.6 |
cg10456459 | 26.49 (24.34, 28.20) | 38.02 (35.68, 43.86) | <0.001 | 32.19 (27.47, 35.90) | 36.44 (27.72, 44.06) | 0.05 | 36.14 (28.20, 39.10) | 32.97 (27.36, 39.06) | 0.5 |
cg03621504 | 20.23 (18.28, 21.37) | 26.25 (23.76, 30.42) | <0.001 | 22.47 (20.74, 26.12) | 23.76 (21.39, 29.92) | 0.2 | 23.66 (20.89, 26.40) | 22.90 (20.88, 26.56) | 0.8 |
Note: Beta values are represented as percentages (beta values times 100). Median differences between groups were tested using a Mann-Whitney U test