Table 1. . Differentially expressed miRNAs by sex in newborns.
|
miRNA hsa-miR- |
MIMAT ID |
Boys |
Girls |
Overall |
LFC1 |
FC2 |
p-value |
|||
|---|---|---|---|---|---|---|---|---|---|---|
| log2 mean expression | Variance | log2 mean expression | Variance | log2 mean expression | Variance | |||||
| 6753-5p |
0027406 |
7.8 |
10.04 |
5.73 |
0.65 |
6.78 |
6.42 |
2.07 |
4.20 |
1.03 × 10-19 |
| 602 |
0003270 |
5.68 |
6.37 |
3.97 |
2.45 |
4.84 |
5.12 |
1.71 |
3.27 |
4.15 × 10-6 |
| 4417 |
0018929 |
6.58 |
5.75 |
4.99 |
2.21 |
5.79 |
4.6 |
1.59 |
3.01 |
3.85 × 10-6 |
| 452-5p |
0001635 |
6.08 |
4.37 |
4.52 |
1.08 |
5.31 |
3.33 |
1.56 |
2.95 |
2.42 × 10-11 |
| 4792 |
0019964 |
11.8 |
3.11 |
10.25 |
1.57 |
11.03 |
2.94 |
1.55 |
2.93 |
1.03 × 10-7 |
| 4739 |
0019868 |
7.96 |
6 |
6.41 |
0.44 |
7.2 |
3.82 |
1.55 |
2.93 |
1.18 × 10-15 |
| 4271 |
0016901 |
7.09 |
6.06 |
5.6 |
0.23 |
6.35 |
3.71 |
1.49 |
2.81 |
9.44 × 10-18 |
| 8071 |
0030998 |
6.55 |
1.67 |
5.11 |
0.63 |
5.84 |
1.67 |
1.44 |
2.71 |
2.30 × 10-16 |
| 3197 |
0015082 |
7.6 |
6.31 |
6.27 |
0.98 |
6.94 |
4.08 |
1.33 |
2.51 |
6.33 × 10-13 |
| 6799-5p |
0027498 |
8.09 |
3.03 |
6.76 |
0.79 |
7.43 |
2.35 |
1.33 |
2.51 |
7.08 × 10-11 |
| 6741-5p |
0027383 |
9.07 |
1.92 |
7.8 |
0.85 |
8.45 |
1.78 |
1.27 |
2.41 |
7.32 × 10-10 |
| 6875-5p |
0027650 |
5.18 |
3.14 |
3.91 |
0.54 |
4.55 |
2.24 |
1.27 |
2.41 |
3.17 × 10-11 |
| 8078 |
0031005 |
7.19 |
5.29 |
5.93 |
0.95 |
6.57 |
3.52 |
1.26 |
2.39 |
1.45 × 10-12 |
| 1292-3p |
0022948 |
8.24 |
2.34 |
7.03 |
1.91 |
7.64 |
2.47 |
1.21 |
2.31 |
2.11 × 10-4 |
| 6780b-5p |
0027572 |
7.19 |
5.08 |
6.04 |
0.32 |
6.62 |
3.03 |
1.15 |
2.22 |
1.74 × 10-12 |
| 3178 |
0015055 |
10.26 |
5.45 |
9.11 |
0.3 |
9.69 |
3.21 |
1.15 |
2.22 |
2.45 × 10-13 |
| 6126 |
0024599 |
10.72 |
3.44 |
9.6 |
0.25 |
10.16 |
2.16 |
1.12 |
2.17 |
6.15 × 10-12 |
| 6877-5p |
0027654 |
5.68 |
1.34 |
4.56 |
0.52 |
5.13 |
1.24 |
1.12 |
2.17 |
6.64 × 10-9 |
| 4449 |
0018968 |
6.16 |
2.09 |
5.06 |
0.52 |
5.62 |
1.6 |
1.1 |
2.14 |
6.36 × 10-9 |
| 4281 |
0016907 |
12.32 |
2.52 |
11.22 |
1.22 |
11.77 |
2.16 |
1.1 |
2.14 |
1.90 × 10-4 |
| 4478 |
0019006 |
6.09 |
1.45 |
5.06 |
0.69 |
5.58 |
1.34 |
1.03 |
2.04 |
1.84 × 10-6 |
| 1914-5p |
0007889 |
4.36 |
1.41 |
3.33 |
0.53 |
3.85 |
1.24 |
1.03 |
2.04 |
1.96 × 10-7 |
| 4516 |
0019053 |
13.87 |
1.71 |
12.87 |
1.54 |
13.37 |
1.86 |
1 |
2.00 |
1.93 × 10-3 |
| 3142 |
0015011 |
7.22 |
1.62 |
6.22 |
0.31 |
6.73 |
1.21 |
1 |
2.00 |
2.82 × 10-9 |
| 663a |
0003326 |
9.84 |
2.52 |
8.85 |
0.54 |
9.35 |
1.77 |
0.99 |
1.99 |
1.30 × 10-7 |
| 663b |
0005867 |
5.95 |
2.87 |
4.97 |
0.76 |
5.46 |
2.05 |
0.98 |
1.97 |
2.13 × 10-6 |
| 8069 |
0030996 |
6.1 |
1.29 |
5.14 |
0.45 |
5.62 |
1.1 |
0.96 |
1.95 |
3.73 × 10-8 |
| 4505 |
0019041 |
6.68 |
0.87 |
5.73 |
0.79 |
6.21 |
1.05 |
0.95 |
1.93 |
9.84 × 10-5 |
| 6729-5p |
0027359 |
6.96 |
2.43 |
6.02 |
0.3 |
6.5 |
1.59 |
0.94 |
1.92 |
2.36 × 10-10 |
| 3940-5p |
0019229 |
6.09 |
2.49 |
5.16 |
0.41 |
5.63 |
1.67 |
0.93 |
1.91 |
2.84 × 10-8 |
| 6798-5p |
0027496 |
6.07 |
1.15 |
5.15 |
0.58 |
5.62 |
1.07 |
0.92 |
1.89 |
2.37 × 10-5 |
| 3652 |
0018072 |
5.13 |
1.88 |
4.24 |
0.29 |
4.69 |
1.28 |
0.89 |
1.85 |
1.13 × 10-8 |
| 6829-5p |
0027558 |
4.85 |
0.75 |
3.97 |
0.5 |
4.41 |
0.82 |
0.88 |
1.84 |
3.60 × 10-6 |
| 6786-5p |
0027472 |
9.05 |
2.86 |
8.18 |
0.26 |
8.62 |
1.75 |
0.87 |
1.83 |
4.08 × 10-9 |
| 4651 |
0019715 |
7.41 |
1.05 |
6.56 |
0.74 |
6.99 |
1.08 |
0.85 |
1.80 |
9.75 × 10-4 |
| 6124 |
0024597 |
6.31 |
1.05 |
5.46 |
0.45 |
5.89 |
0.92 |
0.85 |
1.80 |
7.96 × 10-6 |
| 4448 |
0018967 |
12.1 |
1.03 |
11.26 |
0.83 |
11.69 |
1.1 |
0.84 |
1.79 |
1.17 × 10-2 |
| 3928-3p |
0018205 |
4.08 |
2.18 |
3.25 |
1.08 |
3.67 |
1.79 |
0.83 |
1.78 |
1.51 × 10-2 |
| 149-3p |
0004609 |
8.91 |
1.41 |
8.08 |
0.35 |
8.5 |
1.05 |
0.83 |
1.78 |
1.85 × 10-7 |
| 638 |
0003308 |
8.77 |
2.42 |
7.94 |
0.44 |
8.36 |
1.6 |
0.83 |
1.78 |
1.10 × 10-8 |
| 4787-5p |
0019956 |
10.49 |
1.33 |
9.73 |
0.62 |
10.11 |
1.11 |
0.76 |
1.69 |
3.14 × 10-5 |
| 3656 |
0018076 |
11.38 |
2.84 |
10.64 |
0.75 |
11.02 |
1.93 |
0.74 |
1.67 |
1.58 × 10-5 |
| 3648 |
0018068 |
4.03 |
2.16 |
3.3 |
0.62 |
3.67 |
1.52 |
0.73 |
1.66 |
1.97 × 10-6 |
| 127-3p |
0000446 |
6.41 |
0.52 |
5.68 |
0.57 |
6.05 |
0.67 |
0.73 |
1.66 |
1.30 × 10-3 |
| 4443 |
0018961 |
9.61 |
1.46 |
8.9 |
0.35 |
9.26 |
1.03 |
0.71 |
1.64 |
6.48 × 10-6 |
| 6088 |
0023713 |
7.44 |
0.67 |
6.76 |
0.54 |
7.1 |
0.71 |
0.68 |
1.60 |
1.89 × 10-3 |
| 4488 |
0019022 |
13.06 |
1.97 |
12.39 |
0.86 |
12.73 |
1.52 |
0.67 |
1.59 |
1.91 × 10-3 |
| 4463 |
0018987 |
7.42 |
0.85 |
6.75 |
0.3 |
7.09 |
0.69 |
0.67 |
1.59 |
2.82 × 10-5 |
| 6724-5p |
0025856 |
5.96 |
1.5 |
5.3 |
0.25 |
5.63 |
0.98 |
0.66 |
1.58 |
6.06 × 10-6 |
| 616-5p |
0003284 |
6.35 |
0.7 |
5.69 |
0.48 |
6.02 |
0.69 |
0.66 |
1.58 |
1.26 × 10-3 |
| 4419b |
0019034 |
4.64 |
0.64 |
3.99 |
0.53 |
4.32 |
0.69 |
0.65 |
1.57 |
1.70 × 10-2 |
| 4534 |
0019073 |
5.03 |
0.49 |
4.39 |
0.49 |
4.71 |
0.59 |
0.64 |
1.56 |
1.26 × 10-3 |
| 6086 |
0023711 |
5.37 |
0.39 |
4.74 |
0.28 |
5.06 |
0.43 |
0.63 |
1.55 |
4.62 × 10-5 |
| 4442 |
0018960 |
4.8 |
0.75 |
4.18 |
0.6 |
4.49 |
0.76 |
0.62 |
1.54 |
4.67 × 10-2 |
| 2861 |
0013802 |
10.22 |
1.76 |
9.63 |
0.31 |
9.93 |
1.12 |
0.59 |
1.51 |
3.12 × 10-5 |
| 7845-5p |
0030420 |
4.46 |
1.26 |
3.88 |
0.48 |
4.17 |
0.95 |
0.58 |
1.49 |
3.72 × 10-3 |
| 1469 |
0007347 |
4.45 |
1.96 |
3.87 |
0.43 |
4.16 |
1.27 |
0.58 |
1.49 |
1.06 × 10-5 |
| 1207-5p |
0005871 |
6.51 |
0.59 |
5.93 |
0.38 |
6.22 |
0.57 |
0.58 |
1.49 |
1.70 × 10-3 |
| 6085 |
0023710 |
6.08 |
0.46 |
5.5 |
0.37 |
5.79 |
0.5 |
0.58 |
1.49 |
2.53 × 10-3 |
| 6851-5p |
0027602 |
4.29 |
0.74 |
3.71 |
0.35 |
4 |
0.62 |
0.58 |
1.49 |
1.40 × 10-3 |
| 6727-5p |
0027355 |
6.7 |
1.89 |
6.13 |
0.68 |
6.42 |
1.36 |
0.57 |
1.48 |
2.31 × 10-3 |
| 6894-5p |
0027688 |
5.59 |
0.48 |
5.02 |
0.43 |
5.31 |
0.53 |
0.57 |
1.48 |
1.67 × 10-2 |
| 762 |
0010313 |
9.03 |
1.53 |
8.47 |
0.13 |
8.75 |
0.91 |
0.56 |
1.47 |
1.06 × 10-6 |
| 4481 |
0019015 |
4.5 |
0.61 |
4 |
0.31 |
4.25 |
0.52 |
0.5 |
1.41 |
2.58 × 10-2 |
| 5787 |
0023252 |
10.29 |
1.76 |
9.8 |
0.54 |
10.05 |
1.2 |
0.49 |
1.40 |
2.80 × 10-2 |
| 4763-3p |
0019913 |
6.32 |
0.45 |
5.84 |
0.36 |
6.08 |
0.46 |
0.48 |
1.39 |
5.47 × 10-3 |
| 4674 |
0019756 |
4.66 |
2.61 |
4.19 |
0.65 |
4.43 |
1.68 |
0.47 |
1.39 |
2.23 × 10-4 |
| 6764-3p |
0027429 |
6.02 |
0.41 |
5.55 |
0.27 |
5.79 |
0.39 |
0.47 |
1.39 |
1.05 × 10-2 |
| 127-5p |
0004604 |
7.59 |
0.72 |
7.12 |
0.22 |
7.36 |
0.52 |
0.47 |
1.39 |
8.90 × 10-3 |
| 4497 |
0019032 |
14.53 |
0.84 |
14.06 |
0.39 |
14.3 |
0.67 |
0.47 |
1.39 |
1.52 × 10-2 |
| 566 |
0003230 |
5.93 |
0.42 |
5.47 |
0.36 |
5.7 |
0.44 |
0.46 |
1.38 |
2.23 × 10-2 |
| 6781-5p |
0027462 |
4.4 |
1.29 |
3.95 |
0.43 |
4.18 |
0.91 |
0.45 |
1.37 |
1.12 × 10-2 |
| 1268b |
0018925 |
8.86 |
0.49 |
8.41 |
0.4 |
8.64 |
0.49 |
0.45 |
1.37 |
1.44 × 10-2 |
| 6791-5p |
0027482 |
4.83 |
0.32 |
4.39 |
0.22 |
4.61 |
0.32 |
0.44 |
1.36 |
1.75 × 10-2 |
| 6090 |
0023715 |
10.55 |
1.77 |
10.12 |
0.32 |
10.34 |
1.09 |
0.43 |
1.35 |
9.37 × 10-5 |
| 6756-5p |
0027412 |
5.87 |
0.55 |
5.44 |
0.16 |
5.66 |
0.4 |
0.43 |
1.35 |
1.42 × 10-3 |
| 4690-5p |
0019779 |
4.45 |
0.55 |
4.03 |
0.22 |
4.24 |
0.42 |
0.42 |
1.34 |
1.12 × 10-2 |
| 1227-5p |
0022941 |
9.57 |
0.53 |
9.16 |
0.23 |
9.37 |
0.42 |
0.41 |
1.33 |
6.75 × 10-4 |
| 4758-5p |
0019903 |
4.4 |
0.39 |
4 |
0.29 |
4.2 |
0.38 |
0.4 |
1.32 |
5.54 × 10-3 |
| 6821-5p |
0027542 |
5.52 |
0.8 |
5.13 |
0.32 |
5.32 |
0.6 |
0.39 |
1.31 |
1.72 × 10-2 |
| 4466 |
0018993 |
11.64 |
1.27 |
11.26 |
0.26 |
11.45 |
0.8 |
0.38 |
1.30 |
4.46 × 10-4 |
| 6803-5p |
0027506 |
7.48 |
2.1 |
7.1 |
0.25 |
7.29 |
1.21 |
0.38 |
1.30 |
2.12 × 10-5 |
| 7109-3p |
0028116 |
5.84 |
0.48 |
5.48 |
0.13 |
5.66 |
0.34 |
0.36 |
1.28 |
1.61 × 10-2 |
| 708-5p |
0004926 |
4.79 |
0.25 |
5.16 |
0.31 |
4.97 |
0.31 |
-0.37 |
-1.29 |
9.31 × 10-3 |
| 590-5p |
0003258 |
7.05 |
0.47 |
7.46 |
0.35 |
7.26 |
0.45 |
-0.41 |
-1.33 |
1.76 × 10-2 |
| 1537-3p |
0007399 |
4.78 |
0.45 |
5.21 |
0.31 |
4.99 |
0.42 |
-0.43 |
-1.35 |
1.94 × 10-2 |
| 15a-5p |
0000068 |
13.13 |
0.63 |
13.65 |
0.43 |
13.39 |
0.59 |
-0.52 |
-1.43 |
7.45 × 10-3 |
| 424-3p |
0004749 |
3.99 |
0.43 |
4.54 |
0.35 |
4.26 |
0.46 |
-0.55 |
-1.46 |
9.19 × 10-4 |
| 33a-3p |
0004506 |
3.93 |
0.66 |
4.5 |
0.57 |
4.21 |
0.69 |
-0.57 |
-1.48 |
7.56 × 10-3 |
| 33b-5p |
0003301 |
5.2 |
0.76 |
5.78 |
0.85 |
5.49 |
0.88 |
-0.58 |
-1.49 |
2.29 × 10-2 |
| 33a-5p |
0000091 |
5.86 |
0.79 |
6.46 |
0.48 |
6.16 |
0.72 |
-0.6 |
-1.52 |
3.83 × 10-2 |
| 4454 |
0018976 |
11.37 |
1.14 |
12.44 |
0.71 |
11.9 |
1.21 |
-1.07 |
-2.10 |
1.08 × 10-2 |
| 20a-3p |
0004493 |
4.28 |
2.12 |
5.42 |
0.56 |
4.85 |
1.66 |
-1.14 |
-2.20 |
6.73 × 10-3 |
| 7975 | 0031178 | 8.63 | 4.19 | 10.46 | 1.65 | 9.53 | 3.76 | -1.83 | -3.56 | 1.88 × 10-2 |
FC2: Fold change; LFC1: Log2-fold change; MIMAT: Mature miRNA miRBase accession.