Table 1.
Participant Demographics by Genotype
| FAAH (N=41) | CNR1 (N=41) | |||
|---|---|---|---|---|
| C/C (n=20) | A/C and A/A (n=21) | A/A (n=11) | A/G and G/G (n=30) | |
| % or M ± SD (range) |
% or M ± SD (range) | % or M ± SD (range) |
% or M ± SD (range) | |
| Gender (% female) | 25% | 47.6% | 36.4% | 36.7% |
| Ethnicity (Caucasian) | 85%* | 33%* | 81.8% | 50% |
| Age (years) | 20.7 ± 2.0 (18–25)* | 22.3 ± 2.3 (18–25)* | 21.1 ± 2.3 (18–25) | 21.6 ± 2.3 (18–25) |
| Education (years) | 13.4 ± 1.4 (11–16) | 12.9 ± 1.7 (9–17) | 13.0 ± 1.5 (11–16) | 13.2 ± 1.6 (9–17) |
| Beck Depression Inventory-II (BDI-II) |
6.9 ± 5.3 (0–20) | 4.1 ± 5.1 (0–21) | 4.4 ± 3.2 (0–11) | 5.9 ± 5.9 (0–21) |
| BDI-II (sleep question removed) |
6.0 ± 4.9 (0–19) | 3.7 ± 4.8 (0–20) | 3.8 ± 3.2 (0–11) | 5.2 ± 5.4 (0–20) |
| Past year nicotine use (cigarettes) |
1490.8 ± 2580.0 (0–7350.0) | 645.95 ± 791.9 (0–2399.0) | 2184.6 ± 3246.7 (4–7350.0)* | 645.0 ± 867.8 (0–2890.0)* |
| Past year cannabis use (joints) |
1000.2 ± 1751.5 (13–7343) | 579.9 ± 940.6 (12–4179) | 885.6 ± 1148.4 (42–3895) | 748.0 ± 1490.7 (12–7343) |
| Length of cannabis abstinence (days) |
13.2 ± 7.5 (6–36) | 15.9 ± 13.7 (6–53) | 12.9 ± 8.9 (7–36) | 15.2 ± 11.2 (6–53) |
| Past year alcohol use (standard drinks) |
357.8 ± 379.2 (29–1156) | 188.9 ± 367.2 (2–1724) | 293.2 ± 513.3 (19–1724) | 263.2 ± 325.9 (2–1156) |
| PSQI global score | 7.3 ± 2.0 (5–11) | 6.1 ± 2.0 (4–11) | 6.1 ± 1.7 (4–10) | 6.9 ± 2.2 (4–11) |
| % Disturbed sleep (PSQI global score >5) |
85% | 52.4% | 54.5% | 73.3% |
Note.
*
Group differences: p< .05. PSQI= Pittsburgh Sleep Quality Index. FAAH= Fatty acid amide hydrolase rs324420 C to A single nucleotide polymorphism (SNP); CNR1= CNR1 rs2180619 A to G SNP.