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. Author manuscript; available in PMC: 2017 Feb 2.
Published in final edited form as: Annu Rev Biomed Eng. 2015 Aug 14;17:191–216. doi: 10.1146/annurev-bioeng-071114-040733

Figure 2.

Figure 2

Key attributes of antibodies that must be collectively optimized to generate effective immunoglobulins for different applications. A key challenge is that optimizing one property can lead to deleterious impacts on others.