Table 4.

Meta-analysis of the association between BDNF rs6265 and rs2049046 polymorphism and migraine

rs number	Studies	W Vs M (allele model)		WW + WM Vs MM (dominant model)		WW Vs WM + MM (recessive model)		WW Vs MM (additive model)		WW Vs WM (additive model)
		OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p
rs6265(G/A)	5	0.86 (0.76, 0.99)	0.03	0.85 (0.56, 1.28)	0.42	0.84 (0.72, 0.98)	0.03	0.81 (0.53, 1.22)	0.31	0.85 (0.72, 1.00)	0.04
rs2049046(A/T)	4	0.88 (0.79, 0.98)	0.02	0.89 (0.75, 1.06)	0.18	0.80 (0.67, 0.96)	0.02	0.78 (0.62, 0.97)	0.02	0.81 (0.67, 0.99)	0.03

Abbreviation: W wild allele, M mutant allele, WW wild homozygote, WM heterozygote, MM mutant homozygote