Table 6.

Insertions and Deletions in Coding Regions

	≥3 Human mRNA/EST	≥3 Non-human mRNA/EST	No support
Genome only	1345 (60.3%)	1155 (51.8%)	115 (5.2%)
mRNA only	204 (9.1%)	145 (6.5%)	767 (34.4%)
Genome and mRNA	275 (12.3%)	266 (11.9%)	94 (4.2%)
Neither	407 (18.2%)	665 (29.8%)	NA

Analysis of 2231 frameshift insertions and deletions in alignments of CDS regions of full-length mRNAs to the human genome sequence. Sequences are compared against other human and non-human mRNA and EST sequences that align at this position. Reported are the number of instances in which three or more other human (column 2) or nonhuman (column 3) mRNA or EST sequences agree with each. The last column indicates how many have no other human or nonhuman mRNA or EST support at all. The first row shows the number of times only the genome has the corresponding level of support; the second row, the same for the mRNA. The third row shows how many times both the genome and the mRNA are supported at the level indicated; the last row, when neither have that level of support.