Table 4.

Multivariate Cox proportional hazard analysis for overall survival

Variable	Multivariate analysis
	HR	95% CI	p value
Tumor location
Extremity	1	0.6–2.4	0.47
Central	1.25
Type of operation
Limb salvage	1	1.0–2.2	0.029
Amputation	1.53
Size (cm)
< 8 cm	1	0.8–1.7	0.35
> 8 cm	1.20
Vascular invasion
No	1	1.4–3.3	< 0.0001
Yes	2.17
Chemotherapy necrosis
≥ 90%	1	2.0–4.8	< 0.0001
< 90%	3.12

HR = hazard ratio; CI = confidence interval.