Table I.
Comparison of plasma leptin and adiponectin levels by demographic and clinicopathological characteristics.
| Variables | Leptin (ng/ml), No (%)
|
p-Value | Adiponectin (μg/ml), No (%)
|
p-Value | ||
|---|---|---|---|---|---|---|
| <Median | ≥Median | <Median | ≥Median | |||
| Age group | ||||||
| <62.6 years | 42 (48.8) | 44 (51.2) | 46 (53.5) | 40 (46.5) | ||
| ≥62.6 years | 41 (47.7) | 45 (52.3) | 0.879 | 40 (46.5) | 46 (53.5) | 0.360 |
| Gender | ||||||
| Female | 11 (29.7) | 26 (70.3) | 10 (27.0) | 27 (73.0) | ||
| Male | 72 (53.3) | 63 (46.7) | 0.011 | 76 (56.3) | 59 (43.7) | 0.002 |
| Race/ethnicity | ||||||
| Non-Hispanic White | 34 (41.5) | 48 (58.5) | 44 (53.7) | 38 (46.3) | ||
| Others | 49 (54.4) | 41 (45.6) | 0.089 | 42 (46.7) | 48 (53.3) | 0.359 |
| Hepatitis B virus infection | ||||||
| Negative | 65 (45.5) | 78 (54.5) | 66 (46.2) | 77 (53.8) | ||
| Positive | 18 (62.1) | 11 (37.9) | 0.103 | 20 (68.9) | 9 (31.1) | 0.025 |
| Hepatitis C virus infection | ||||||
| Negative | 30 (41.7) | 42 (58.3) | 46 (63.9) | 26 (36.1) | ||
| Positive | 53 (53.0) | 47 (47.0) | 0.142 | 40 (40.0) | 60 (60.0) | 0.002 |
| Alcohol drinking history | ||||||
| No | 62 (50.0) | 62 (50.0) | 62 (50.0) | 62 (50.0) | ||
| Yes | 21 (43.8) | 27 (56.2) | 0.462 | 24 (50.0) | 24 (50.0) | 1.000 |
| Cigarette smoking | ||||||
| Never | 31 (48.4) | 33 (51.6) | 31 (48.4) | 33 (51.6) | ||
| Ever | 48 (48.0) | 52 (52.0) | 0.956 | 50 (50.0) | 50 (50.0) | 0.845 |
| Diabetes mellitus history | ||||||
| No | 55 (56.7) | 42 (43.3) | 44 (45.4) | 53 (54.6) | ||
| Yes | 28 (37.3) | 47 (62.7) | 0.012 | 42 (56.0) | 33 (44.0) | 0.166 |
| Body mass index at enrollment (kg/m2) | ||||||
| <30 | 42 (80.8) | 10 (19.2) | 19 (36.5) | 33 (63.5) | ||
| ≥30.0 | 34 (32.4) | 71 (67.6) | <0.0001 | 58 (55.2) | 47 (44.8) | 0.027 |
| Waist to hip ratio | ||||||
| <0.953 | 42 (55.3) | 34 (44.7) | 36 (47.4) | 40 (52.6) | ||
| ≥0.953 | 31 (40.3) | 46 (59.7) | 0.063 | 40 (51.9) | 37 (48.1) | 0.571 |
| α-fetoprotein (ng/ml) | ||||||
| <48 | 37 (43.5) | 48 (56.5) | 41 (48.2) | 44 (51.8) | ||
| ≥48 | 46 (52.9) | 41 (47.1) | 0.220 | 45 (51.7) | 42 (48.3) | 0.647 |
| Child-Pugh class | ||||||
| A | 52 (49.1) | 54 (50.9) | 70 (66.0) | 36 (34.0) | ||
| B | 30 (46.2) | 35 (53.8) | 0.712 | 16 (24.6) | 49 (75.4) | <0.0001 |
| Metastasis | ||||||
| Negative | 70 (49.0) | 73 (51.0) | 71 (49.7) | 72 (50.4) | ||
| Positive | 10 (52.6) | 9 (47.4) | 0.763 | 10 (52.6) | 9 (47.4) | 0.807 |
| Milan criteria | ||||||
| Within | 28 (43.1) | 37 (56.9) | 34 (52.3) | 31 (47.7) | ||
| Outside | 55 (51.4) | 52 (48.6) | 0.289 | 52 (48.6) | 55 (51.4) | 0.637 |
| Barcelona clinic liver cancer stage | ||||||
| 0, A | 30 (48.4) | 32 (51.6) | 30 (48.4) | 32 (51.6) | ||
| B, C | 53 (48.2) | 57 (51.8) | 0.979 | 56 (50.9) | 54 (49.1) | 0.751 |
| Cancer antigen 19-9 (U/ml) | ||||||
| <38.0 | 36 (43.9) | 46 (56.1) | 45 (54.9) | 37 (45.1) | ||
| ≥38.0 | 46 (52.3) | 42 (47.7) | 0.275 | 40 (45.5) | 48 (54.5) | 0.220 |
| Liver transplantation | ||||||
| No | 70 (51.9) | 65 (48.1) | 68 (50.4) | 67 (49.6) | ||
| Yes | 13 (35.1) | 24 (64.9) | 0.071 | 18 (48.7) | 19 (51.43) | 0.853 |