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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Anticancer Res. 2016 Oct;36(10):5307–5314. doi: 10.21873/anticanres.11103

Table III.

Demographic, clinicopathological factors and leptin, adiponectin markers in association with hepatocellular carcinoma survival among those without liver transplant.

Variables Survival status, No (%)
p-Value
Alive Dead
Age group
 <62.6 years 23 (36.5) 40 (63.5)
 ≥62.6 years 25 (34.7) 47 (65.3) 0.829
Gender
 Female 10 (33.3) 20 (66.7)
 Male 38 (36.2) 67 (63.8) 0.773
Race/ethnicity
 Non-Hispanic White 17 (27.0) 46 (73.0)
 Others 31 (43.1) 41 (56.9) 0.052
Hepatitis B virus infection
 Negative 35 (31.5) 76 (68.5)
 Positive 13 (54.2) 11 (45.8) 0.036
Hepatitis C virus infection
 Negative 20 (33.9) 39 (66.1)
 Positive 28 (36.8) 48 (63.2) 0.411
Alcohol drinking history
 No 33 (33.0) 67 (67.0)
 Yes 15 (42.9) 20 (57.1) 0.294
Cigarette smoking
 Never 19 (36.5) 33 (63.5)
 Ever 27 (35.1) 50 (64.9) 0.864
Diabetes mellitus history
 No 28 (38.9) 44 (61.1)
 Yes 20 (31.8) 43 (68.3) 0.387
Body mass index at enrollment (kg/m2)
 <30 18 (40.9) 26 (59.1)
 ≥30.0 25 (32.1) 53 (67.9) 0.325
Waist to hip ratio
 <0.953 23 (38.3) 37 (61.7)
 ≥0.953 17 (28.8) 42 (71.2) 0.272
α-fetoprotein (ng/ml)
 <48 26 (44.8) 32 (55.2)
 ≥48 22 (28.6) 55 (71.4) 0.051
Child-Pugh class
 A 33 (40.2) 49 (59.8)
 B 14 (26.9) 38 (73.1) 0.115
Metastasis
 No 44 (41.1) 63 (58.9)
 Yes 2 (10.5) 17 (89.5) 0.011
Milan criteria
 Within 23. (59.0) 16 (41.0)
 Outside 25 (26.0) 71 (74.0) <0.001
Barcelona clinic liver cancer stage
 0, A 23 (57.5) 17 (42.5)
 B, C 25 (26.3) 70 (73.7) 0.001
Cancer antigen 19-9 (U/ml)
 <38.0 24 (38.1) 39 (61.9)
 ≥38.0 23 (32.9) 47 (67.1) 0.528
Leptin (ng/ml)
 <Median 26 (37.1) 44 (62.9)
 ≥Median 22 (33.9) 43 (66.1) 0.689
Adiponectin (μg/ml)
 <Median 28 (41.2) 40 (58.8)
 ≥Median 20 (29.9) 47 (70.1) 0.169