Table 2.
Mental Health Characteristics for the Matched SLE/MCTD and T1D Cohorts
| SLE/MCTD N=50 | T1D N=50 | OR (95%CI) reference group= T1D | ||
|---|---|---|---|---|
| Unadjusted | Adjusted | |||
| Any symptom (depression and/or anxiety), N (%) | 17 (34) | 19 (38) | - | - |
| Depression, N (%) | 10 (20) | 13 (26) | 0.8 (0.4-1.6) p=0.48 | 0.4 (0.2-1.0) p=0.06 |
| PHQ-9 score in depressed, mean (SD) | 11 (5) | 8 (5) | - | - |
| Suicidal ideation, N (%) | 7 (14) | 8 (16) | 0.9 (0.4-2.1) p=0.76 | 0.3 (0.1-0.8) p=0.02 |
| Anxiety, N (%) | 11 (22) | 16 (32) | 0.7 (0.3-1.4) p=0.31 | - |
| SCARED score in anxious, median (IQR) | 31 (28, 41) | 33 (30, 39) | - | - |
| Anxiety category in anxious, N (%) | ||||
| Generalized anxiety | 8 (72) | 4 (25) | - | - |
| Panic/Somatic Symptoms | 4 (36) | 7 (44) | - | - |
| Separation Anxiety | 7 (63) | 5 (31) | - | - |
| Social Anxiety | 7 (63) | 8 (50) | - | - |
| School Avoidance | 4 (36) | 2 (13) | - | - |
| Co-morbid depression & anxiety, N (%) | 4 (24) | 4 (21) | - | - |
| Mental health treatment in symptomatic, N (%) | 4 (24) | 10 (53) | 0.4 (0.2-1.1) p=0.07 | - |
Mental health characteristics for the matched SLE/MCTD and T1D cohorts are shown. One SLE/MCTD and 6 T1D subjects positive for depression (due to suicidal ideation) but not meeting categorization criteria (due to total PHQ-9 score <5) were omitted. SCARED score was missing for 1 SLE/MCTD subject. Estimates from analyses separately comparing depression, suicidal ideation and anxiety prevalence between the SLE/MCTD and T1D (reference group) cohorts are shown. The covariates included in the adjusted models for depression and suicidal ideation are race/ethnicity and disease duration.