Table 1. Baboon responses to experimental pertussis infection.
| Baboon | Active B. br infection a) | Anti-Fha titer>100 IU/mlb) | Anti-LOS absorbance >0.1 b) | WBC <13,000/µlc) | CFU <106/mlc) | Response to Pertussis Infection d) |
|---|---|---|---|---|---|---|
| C1 | - | - | - | - | - | typical |
| C2 | yes | - | - | - | - | excluded |
| C3 | yes | - | - | yes | - | excluded |
| C4 | yes* | yes | yes | yes | yes | excluded |
| C5 | - | yes | yes | yes | yes | atypical |
| C6 | - | - | - | - | - | typical |
| C7 | - | - | - | - | - | typical |
| T1 | - | yes | yes | yes | yes | atypical |
| T2 | - | yes | yes | yes | yes | atypical |
| T3 | - | yes | yes | yes | yes | atypical |
| T4 | - | yes | yes | yes | yes | atypical |
| T5 | yes | yes | yes | - | yes | excluded |
| T6 | - | yes | yes | - | yes | atypical |
| T7 | - | - | - | - | - | typical |
| T8 | - | - | - | - | - | typical |
a) B. br =B. bronchiseptica; -animal did not exhibit this behavior ; *=B. br infection identified by standard microbiological techniques. b) Anti-Fha and anti-LOS titers were measured in serum samples collected on day 9/10 after experimental pertussis infection. c) WBC and CFU values were collected from day 2/3 serum samples. d) Typical baboon responses to experimental pertussis infection are defined by WBC >13,000 /µl, CFU >106/ml on day 2/3 and low Fha and LOS serum titers; animals with known or suspected B. bronchiseptica infection were excluded from this classification.