Table 1.
Liposome Formulation | Liposome Composition | Size (nm) | Zeta Potential (mV) | Drug Incorporation (mol%) |
---|---|---|---|---|
DOX-L | 55:45 DSPC:Chol | 154.5 ± 5.0 | −9.55 ± 3.56 | 1.08 ± 0.16 |
+DOX-L | 80:10:10 DSPC:DOTAP:Chol | 155.6 ± 5.3 | 39.93 ± 4.81 | 0.96 ± 0.13 |
5FU-L | 80:10:10 DSPC:DOTAP:Chol | 173.5 ± 43 | 41.7 ± 9.8 | 0.7 ± 0.2 |
5FURW-L | 80:10:10 DSPC:DOTAP:Chol | 163.8 ± 17.2 | 32.2 ± 6.5 | 26.6 ± 2.4 |
Data expressed as mean ± SD (N≥3)