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. Author manuscript; available in PMC: 2017 May 10.
Published in final edited form as: J Control Release. 2016 Mar 24;229:154–162. doi: 10.1016/j.jconrel.2016.03.027

Table 2.

Physical and chemical properties of liposomes containing both 5FURW and DOX.

Liposome Formulation R (5FURW:DOX) DOX Incorporation (mol%) 5FURW Incorporation (mol%) Size (nm) Zeta Potential (mV)
ant DAFODIL 12.2 0.45 ± 0.02 5.47 ± 0.94 156.9 ± 5.7 36.2 ± 0.5
-PEG DAFODIL 0.18 7.75 ± 0.09 1.41 ± 0.47 149.8 ± 15.1 35.7 ± 4.3
DAFODIL 0.15 14.82 ± 0.69 2.17 ± 0.23 168.8 ± 18.7 −23.0 ± 3.0

Lipid composition was 80:10:10 DSPC:DOTAP:Chol, except for DAFODIL, which consisted of 75:5:10:10 DSPC:mPEG-DSPE:DOTAP:Chol. Drug loadings and DLS measurements are reported as mean ± SD (N≥3).