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. 2017 Feb 2;12(2):e0165363. doi: 10.1371/journal.pone.0165363

Table 1. Number of animals showing seizures or interictal spikes, and average seizure duration.

Animal no. Treatment Gender Previously observed violent movements # Seizures Average seizure duration (seconds) Interictal spikes #/hour
73 SLV M No 13 123 76
76 SLV M No 2 120 7
89 SLV M Yes 1 101 83
183 SLV F Yes 1 200 57
195 SLV F Yes 4 97 67
199 SLV F Yes 21 46 149
83 SLV M Yes - - 80
88 SLV M Yes - - 48
182 SLV F Yes - - 19
71, 72, 94, 94 SLV M No - - -
81, 82, 97 SLV M Yes - - -
175, 178, 185, 198, 200 SLV F No - - -
188, 191, 194 SLV F Yes - - -
16 Control M - - - 16
1, 10, 18, 30 Control M - - - -
101, 104, 109, 110, 118, 128 Control F - - - -

6 animals out of 24, all treated with SLV326, showed between 1 and 21 seizures during the 24h recording period. All these animals also showed interictal spikes. 3 more SLV treated animals showed interictal spikes as well, but did not display any seizures. In the control group 1 animal had interictal spikes, although these were not generalized, in contrast to the generalized spikes seen in the SLV326 group.