Table 1. Number of animals showing seizures or interictal spikes, and average seizure duration.
Animal no. | Treatment | Gender | Previously observed violent movements | # Seizures | Average seizure duration (seconds) | Interictal spikes #/hour |
---|---|---|---|---|---|---|
73 | SLV | M | No | 13 | 123 | 76 |
76 | SLV | M | No | 2 | 120 | 7 |
89 | SLV | M | Yes | 1 | 101 | 83 |
183 | SLV | F | Yes | 1 | 200 | 57 |
195 | SLV | F | Yes | 4 | 97 | 67 |
199 | SLV | F | Yes | 21 | 46 | 149 |
83 | SLV | M | Yes | - | - | 80 |
88 | SLV | M | Yes | - | - | 48 |
182 | SLV | F | Yes | - | - | 19 |
71, 72, 94, 94 | SLV | M | No | - | - | - |
81, 82, 97 | SLV | M | Yes | - | - | - |
175, 178, 185, 198, 200 | SLV | F | No | - | - | - |
188, 191, 194 | SLV | F | Yes | - | - | - |
16 | Control | M | - | - | - | 16 |
1, 10, 18, 30 | Control | M | - | - | - | - |
101, 104, 109, 110, 118, 128 | Control | F | - | - | - | - |
6 animals out of 24, all treated with SLV326, showed between 1 and 21 seizures during the 24h recording period. All these animals also showed interictal spikes. 3 more SLV treated animals showed interictal spikes as well, but did not display any seizures. In the control group 1 animal had interictal spikes, although these were not generalized, in contrast to the generalized spikes seen in the SLV326 group.