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Generation of transgenic mice expressing PHveCIg. (A) Schematic representation of the transgene. The PHveCIg gene is under the control of the CAG promoter. The extracellular domain of nectin-1 consists of one V domain and two C domains. Cleavage sites for restriction enzyme SalI are indicated. (B) Western blot analysis of sera from the transgenic (Tg) mice. The arrow indicates the position of detected PHveCIg.
